Kynurenine 3-monooxygenase (Protein name
), KMO_PIG from NCBI database.
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General Annotation
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Antigen Annotation
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3D
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Predicted Eptitope
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Vaild Sequence
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Gene name:
KMO;
Protein name:
Kynurenine 3-monooxygenase;
Alternative:
Kynurenine 3-hydroxylase;Fpk;
Organism:
Pig (Sus scrofa).
General Annotation
Sub Unit:
N/A
Function:
Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract.
Subcellular Location:
Mitochondrion outer membrane
Multi-pass membrane protein
Polyclonal Antibody for Pig Kynurenine 3-monooxygenase
Monoclonal Antibody for Pig Kynurenine 3-monooxygenase
Monoclonal Antibody for Pig Kynurenine 3-monooxygenase
Monoclonal Antibody for Pig Kynurenine 3-monooxygenase
Monoclonal Antibody for Pig Kynurenine 3-monooxygenase
Protein for Pig Kynurenine 3-monooxygenase
Protein for Pig Kynurenine 3-monooxygenase
Protein for Pig Kynurenine 3-monooxygenase
Protein for Pig Kynurenine 3-monooxygenase
R&D Technical Data
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s
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Precision
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Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.
Intra-Assay CV: ≤7.3%
Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.
Inter-Assay CV: ≤8.4%
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Recovery
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Recovery was determined by spiking various levels of KMO into serum and plasma .
Sample Type
Average(%)
Recovery Range(%)
Serum
101
92-106
Plasma
99
95-105
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Linearity
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The linearity of the kit was assayed by testing samples spiked with appropriate concentration of KMO and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.
Sample
1：2
1:4
1:8
1:16
serum(n=5)
95-107%
93-110%
96-105%
98-104%
EDTA plasma(n=5)
90-108%
92-106%
91-107%
92-105%
heparin plasma(n=5)
93-104%
94-106%
93-104%
94-106%
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Vaild Sequence:
